GDUFA Research Outcomes

Topical Products

This section contains scientific publications, presentations, and posters arising from GDUFA-funded research relevant to locally acting generic products administered via the topical route, including topical dermatological products.

• All(374)
• Posters(145)
• Presentations(185)
• Papers(44)

• Evaluation Of Water Activity (Aw) As A Critical Quality Attribute Of Topical Dosage Forms

  Murthy, Narasimha

• In Vitro-In Vivo Relationships (IVIVR) For Transdermal Delivery Of Nicotine From Patches

  Alinaghi, Azadeh; Cheruvu, Hanumanth; Liu, Xin; Anissimov, Yuri; Kuswahyuning, Rina; Ghosh, Priyanka; Grice, Jeffrey; Raney, Sam; Roberts, Michael

• Does Vehicle Evaporation Affect Drug Distribution within Different Phases of Topically Applied Emulsion? A Modeling Case Study with Clindamycin Phosphate Lotion

  Alam, Khondoker; Tsakalozou, Eleftheria; Babiskin, Andrew; Ghosh, Priyanka; Ramezanli, Tannaz; Jiang, Ying; Niu, Mengmeng; Zhao, Liang

• Development of an In Vitro Release Method for Mechlorethamine Hydrochloride Topical Gel

  Ako Adounvo, Ann Marie; Niu, Mengmeng; Ghosh, Priyanka; Ashraf, Muhammad; Zidan, Ahmed

• A Mechanistic Evaluation of How Metamorphosis of a Topical Dosage Form Impacts Permeation

  Ajjarapu, S; Rangappa, S; Ghosh, Priyanka; Kelchen, Megan; Raney, Sam; Urena-Benavides, EE; Maibach, H; Narasimha Murthy, S

• A Mechanistic Evaluation of the Impact of Formulation Viscosity and Fractional Solubility on Drug Release and Permeation

  Ajjarapu, S; Rangappa, S; Ghosh, Priyanka; Kelchen, Megan; Raney, Sam; Urena-Benavides, EE; Maibach, H; Narasimha Murthy, S

• The Impact of the Metamorphosis of Topical Formulations on Bioavailability

  Ajjarapu, S; Rangappa, S; Ghosh, Priyanka; Kelchen, Megan; Raney, Sameersingh; Repka, M A; Maibach, H; Narasimha Murthy, S

• Method Development and Optimization of an In Vitro Permeation Test (IVPT) to Compare the Rate and Extent of Drug Permeation from Topical Drug Products

  Ajjarapu, S; Rangappa, S; Raney, S G; Repka, M A; Murthy, S N

• A Novel Strategy for the Efficient Modulation of Topical Drug Delivery to Validate the Sensitivity of an In Vitro Permeation Test (IVPT)

  Ajjarapu, S; Rangappa, S; Ghosh, P; Raney, S G; Murthy, S N

• Metronidazole Crystal Patterns formed during the Metamorphosis of Topical Carbopol Gels

  Ajjarapu, S; Rangappa, S; Deboyace, K; Wildfong, P; Murthy, S N