Dynamic Change in pH by Low Buffer Capacity of Gastrointestinal Fluids Along the Human Gastrointestinal Tract: Implications for In Vivo Dissolution and Absorption of Ionizable Compounds

Author/sHens, Bart; Tsume, Yasuhiro; Bermejo, Marival; Paixao, Paulo; Koenigsknecht, Mark; Baker, Jason; Hasler, William; Lionberger, Robert; Fan, Jianghong; Dickens, Joseph; Shedden, Kerby; Wen, Bo; Wysocki, Jeffrey; Loebenberg, Raimar; Lee, Allen; Frances, Ann; Amidon, Greg; Yu, Alex; Benninghoff, Gail; Salehi, Niloufar; Talattof, Arjang; Sun, Duxin; Amidon, Gordon L

Date:11/14/2017

Meeting Name:AAPS Annual Meeting

State:CA

City:San Diego